Skip to main content
. Author manuscript; available in PMC: 2009 Aug 7.
Published in final edited form as: Alcohol Clin Exp Res. 2009 May 4;33(8):1450–1459. doi: 10.1111/j.1530-0277.2009.00975.x

Figure 5. Gene expressions of IL-6 family members in rat plantaris.

Figure 5

Real time PCR analyses were performed on several members of the IL-6 family of cytokines in plantaris muscles from rats chronically fed alcohol (EtOH) for 35 weeks. IL-6 and OSM were strongly induced in plantaris muscles from EtOH-fed rats (A and B, respectively). Procysteine (PRO) supplementation attenuated IL-6 induction in plantaris muscles from alcohol-fed rats. Gene expression of (C) ciliary neurotrophic factor (CNTF) and (D) cardiotrophin-1 (CT1) were increased in plantaris muscles from the EtOH-PRO group. Data are represented as means ± range of potential values based on the 2-ΔΔCT method (Otis et al., 2007; Otis et al., 2008a, b) and expressed as fold changes relative to controls (n=6-7 rats/group). Significance was accepted at p ≤ 0.05. *, compared to control group. #, compared to EtOH group.