Figure 1.

HSVcre vectors mediate hippocampal recombination. (A) The CAG-CATZ reporter construct. (B) After delivery of HSVcre or HSVgfpcre, the hippocampus was excised and analyzed for β-gal. The data are the percentage increase of activity compared with nontransgenic animals infected with HSVcre or HSVgfpcre. (C) Confocal images of hippocampal neurons from CAG-CATZ mice infected with HSVgfpcre. The green image represents the eGFP whereas the red image represents β-gal. The combined channel illustrates β-gal in GFP+ cells. (D) Cell counts. β-gal, GFP+, and double-positive cells were enumerated.