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. 2000 Nov 14;97(24):13378–13383. doi: 10.1073/pnas.230169397

Figure 2.

Figure 2

Regulated NGF levels in arecoline-treated mice. Adult NGFXAT mice received HSVcre or HSVlac. Months later, animals received arecoline hydrobromide or saline before sacrifice. NGF in the medial septum and hippocampus was measured by ELISA. Septal HSVcre vs. HSVlac saline treated P = 0.013; hippocampal HSVcre vs. HSVlac saline treated P < 0.0001; HSVlac hippocampus vs. septum saline treated P = 0.0076; HSVcre hippocampus vs. septum P = 0.0001; HSVcre septum arecoline treated vs. HSVcre septum saline P = 0.0013; HSVlac hippocampus arecoline vs. HSVlac saline P < 0.0001; HSVcre hippocampus arecoline vs. HSVcre saline P < 0.0001.