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Effect of the caspase-3 inhibitor Z-DEVD-FMK on apoptosis. (A) Effect of graded concentrations of Z-DEVD-FMK on survival of granule cells. PACAP (10−7 M) was used as an internal control. *, P < 0.05; ***, P < 0.001 vs. control. (B) Representative gel electrophoresis illustrating the effect of Z-DEVD-FMK on DNA laddering. Ctrl, control; MW, molecular weight markers in base pairs.
