. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Hum Genet. 2008 Oct 30;124(5):515–524. doi: 10.1007/s00439-008-0578-5

Table 1.

Demographic, clinical, and laboratory characteristics of the study participants

Characteristic	Non-SMA	SMA	P
No. of participants	238	137	N/A
Gender (n, %)
Male	121 (50.8)	70 (51.1)	0.524^a
Female	117 (49.2)	67 (48.9)	0.524^a
Age (mos.)	11.00 (7.00-16.00)	8.00 (6.00-14.00)	0.009^b
Axillary temperature (°C)	37.5 (36.8-38.7)	37.5 (36.8-38.5)	0.989^b
Hemoglobin (g/dL)	8.30 (7.60-10.60)	5.00 (4.60-5.60)
Parasite density (/μL)	22,628 (4,031-63,359)	25,738 (6, 848-56, 123)	0.852^b
HDP (n, %)	165 (69.3)	137 (67.9)	0.429^a

Data are median (interquartile range, IQR) unless otherwise stated.

Abbreviations: HDP, high-density parasitemia (≥10,000 parasites/μL); SMA, severe malarial anemia (Hb<6.0 g/dL, with any density parasitemia) (McElroy et al. 1999); Non-SMA, non-severe malarial anemia (Hb≥6.0 g/dL, with any density parasitemia.

Statistical significance determined by Chi-square analysis.

Statistical significance determined by Mann-Whitney U test. Statistical testing for differences in Hb levels between SMA and non-SMA was not provided because stratification of these groups was based on Hb levels and presence of parasitemia.