. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Hum Genet. 2008 Oct 30;124(5):515–524. doi: 10.1007/s00439-008-0578-5

Table 4.

Distribution of IL-10 promoter haplotypes in children with malaria

Haplotype (-1082/-819/-592)		Non-SMA (n=238)	SMA (n=137)	P
GCC	1	153 (64.3)	76 (55.5)	0.048^a
	0	85 (35.7)	61 (44.5)
ACC	1	84 (35.3)	51 (37.2)	0.395^a
	0	154 (64.7)	86 (62.8)
ATC	1	10 (4.2)	8 (5.8)	0.316^a
	0	228 (95.8)	129 (94.2)
ATA	1	142 (59.7)	81 (59.1)	0.502^a
	0	96 (40.3)	56 (40.9)

Parasitemic children (n=375) were stratified based on their IL-10 promoter haplotypes (-1082/-819/-592). 1=Presence of haplotype, 0=Absence of haplotype. Data are presented as proportions (n, %).

Abbreviations: SMA, severe malarial anemia (Hb<6.0 g/dL, with any density parasitemia) (McElroy et al. 1999); Non-SMA, non-severe malarial anemia (Hb≥6.0 g/dL, with any density parasitemia).

Chi-square analysis.