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. 2009 Jun 9;2:6. doi: 10.3389/neuro.16.006.2009

Table 2.

Covalent coupling of AM with biomaterials.

Biomaterial/AM Reactive groups In vitro cell line In vivo location References
Methacrylamide chitosan/YIGSR/IKVAV –SH SCG (Yu et al., 2007)
Poly(dex-MA-co-AEMA)/RGD/YIGSR/IKVAV –SH DRG (Levesque and Shoichet, 2006)
–NH2
Poly(HEMA-co-AEMA)/YIGSR/IKVAV –SH DRG (Yu and Shoichet, 2005)
–NH2
Agarose/RGD/YIGSR/IKVAV –OH DRG (Bellamkonda et al., 1995)
PC12
Hyaluronan/Laminin –OH SD F rat brain (Hou et al., 2005)
Dextran/RGD/IKVAV –OH PC12 (Massia et al., 2004)
–CHO GB
Methylcellulose/laminin –OH RC (Stabenfeldt et al., 2006)
–CHO
Chitosan/YIGSR/IKVAV –OH SD M rat brain (Suzuki et al., 2003)
–COOH
Hyaluronan/poly-D-lysine –OH RC SD rat brain (Tian et al., 2005)
Chitosan/poly-D-lysine –NH2 Fetal MC (Crompton et al., 2007)
–OH photo
Agarose/collagen –NH2 photo RC (Cullen et al., 2007)
Poly(tetrafluoroethylene-co-hexafluropropylene)/YIGSR/IKVAV/RGD –OH EHC (Tong and Shoichet, 1998b)
–COOH
Poly(tetrafluoroethylene-co-hexafluropropylene)/YIGSR/IKVAV/RGD and combination of YIGSR/IKVAV –NH2 EHC (Tong and Shoichet, 1998a, Tong and Shoichet, 2001)
Alginate/YIGSR –COOH NB2a (Dhoot et al., 2004)
Poly-L-lactic acid/laminin –COOH PC12 (Koh et al., 2008)
Poly(lactide-co-glycolide)/laminin –COOH SC (Huang et al., 2007)
Chitosan/laminin –OH SC (Huang et al., 2007)
–COOH
Glassy carbon/laminin/laminin-derived peptides –COOH ERGCs (chick) (Huber et al., 1998)
e-poly(tetrafluroethylene)/laminin-derived peptides –SH DRG (Shaw and Shoichet, 2003)
–NH2

DRG: dorsal root ganglion, SCG: superior cervical ganglion, SC: Schwann cells, RC: rat cortical neurons, MC: mouse cortical neurons, EHC: embyronic HippoAMpal neurons, ERGC: embryonic retinal ganglion cells, GB: glioblastoma, SD: Sprague Dawley, F: female, M: male.