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In situ detection of miR-222 in squamous cell cancer of the lung. MiR-221 and 222 are commonly found in cancers, and can impact similar targets. MiR-222 was detected in most of the malignant cells of this squamous cell cancer of the lung using a digoxigenin-tagged LNA probe (panel A); the signal is blue and the counterstain pink. In comparison, miR-222 was not evident in the cells of this section of the adjacent normal lung (panel B).
