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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: J Immunol. 2009 Jun 15;182(12):7353–7363. doi: 10.4049/jimmunol.0900657

Figure 5.

Figure 5

Th17-polarized effectors retain defining aspects of their phenotype in vivo following flu challenge. (A) IFNγ and IL-17 staining of Th1 and Th17 effectors +/− peptide stimulation, and (B) IFNγ, IL-4, IL-17, IL-21 and IL-22 measured in 24 h supernatants of indicated effectors stimulated with APC and peptide. (C) Message for T-bet, GATA-3, and ROR-γt in polarized effectors. (D) Granzyme B staining of Th1 and Th17 effectors prior to and d3 following adoptive transfer and flu infection. (E) IFNγ and IL-17 staining of Th1 and Th17 HNT effectors in lungs 3d after transfer and flu infection. A-B are representative of 4 independent exp, D-E of 3 similar exp.