Table 2.
Methodological issues in included studies
| Author, year | Randomization | Allocation concealment | ITT | Description of margin of equivalence | Blinding status |
|---|---|---|---|---|---|
| Netland 200136 | Yes | Yes | Yes | Yes | Yes |
| Arcieri 200532 | Yes | Yes | No | No | Yes |
| Cantor 200626 | Yes | Yes | Yes | Yes | Yes |
| Cardascia 200334 | No | No | No | No | Yes |
| Noecker 2003a41 | Yes | Yes | Yes | Yes | Yes |
| Koz 200728 | No | No | No | Yes | Yes |
| Noecker 2003b38 | Yes | Unclear | No | No | Yes |
| Noecker 200637 | Yes | No | Yes | No | Yes |
| Dirks 200639 | Yes | Unclear | No | No | Yes |
| Gandolfi 200140 | Yes | Unclear | Yes | Yes | Yes |
| Parrish 200331 | Yes | Yes | Yes | Yes | Yes |
| Cellini 200430 | Yes | Unclear | No | No | Yes |
| Parmaksiz 200635 | Yes | Unclear | No | No | Yes |
| Mundorf 200442 | No | No | No | No | Yes |
| Hepsen 200729 | No | No | No | No | Yes |
| Topouzis 200733 | Yes | No | Yes – for safety analysis only | Yes | Yes |
Abbreviation: ITT, intention to treat.