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CL synthase (CLS) activity and real time PCR from LV tissue. (A) Activity from SHHF rats; (B) CLS mRNA from SHHF rats; and (C) CLS mRNA in human nonfailing (NF) or idiopathic dilated cardiomyopathy (IDC). All PCR data is expressed as mean ± SEM with the young rats or NF humans as 100%. N = 4 (rats) and 8 (humans) per group. *P < 0.05 vs. 2-month SHHF rats or NF humans. SHHF, spontaneously hypertensive heart failure.
