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Alterations in mitochondrial products formed in SHHF rat heart during de novo synthesis and remodeling of cardiolipin
| Specific activity (pmol/min/mg) | 2 months | 5 months | 22 months |
|---|---|---|---|
| PA + PG formed | 78.5 ± 5.2 | 43.0 ± 1.3a | 41.1 ± 4.3a |
| MLCL formed | 17.3 ± 1.2 | 8.8 ± 0.3b | 11.0 ± 0.5a |
Values are mean ± SEM. MLCL, monolysocardiolipin; PA, phosphatidic acid; PG, phosphatidylglycerol; SHHF, spontaneously hypertensive heart failure.
P < 0.01 vs. 2 month.
P < 0.001 vs. 2 month.
