Effects of genistein and selenite on Akt, p53, p21waf1, and Bax in LNCaP and PC3 cells. A and B: Western blot analysis of total AKT, phosphorylated AKT at serine 473 [p-AKT(Ser 473)], total p53, phosphorylated p53 at serine 15 [p-p53(Ser 15)], p21waf1, and Bax in LNCaP cells and PC3 cells. Cells were treated with selenite (Sel) or genistein (Gen) for 24 h, and 50 µg proteins were loaded for the assay. The results shown here is one representative of 3 repeated experiments. DMSO, dimethyl sulfoxide.