Table 1.
Striatal cell types
| cell type: | abundance1: | Rinput: | Vrest2: | axonal targets: | key metabotropic receptors: |
references: |
|---|---|---|---|---|---|---|
| striatonigral MSN | 49 % | <100 MΩ | −80 to −90 mV |
GPi, SNr | D1, M1, M4, mGluR1/5 |
(Cepeda et al., 2008; Hersch et al., 1994; Ince et al., 1997; Kreitzer and Malenka, 2007) |
| striatopallidal MSN | 49 % | <100 MΩ | −80 to −90 mV |
GPe | D2, A2A, M1, mGluR1/5 |
(Cepeda et al., 2008; Hersch et al., 1994; Kreitzer and Malenka, 2007; Pollack et al., 1993) |
| FS interneuron | 0.5 % | <100 MΩ | −80 mV | MSNs | D5 | (Centonze et al., 2003b; Kawaguchi, 1993) |
| LTS interneuron | 1.5 % | >200 MΩ | −60 mV | MSNs | D1-like | (Centonze et al., 2002; Kawaguchi, 1993) |
| cholinergic interneuron | 0.5 % | >200 MΩ | −60 mV | MSNs, FS interneurons |
D2, D5, M2, M4 | (Kawaguchi, 1993; Koos and Tepper, 2002; Wilson et al., 1990; Yan and Surmeier, 1996) |
1
Abundance based on discussion in (Rymar et al., 2004), rounded to the nearest half-percent. Fifty percent of MSNs were assumed to be striatonigral (Huang et al., 1992). LTS interneurons were assumed to include both somatostatin- and calretinin-positive subtypes.
2
Experimental variability due to different extracellular potassium concentrations