The tryptic digestion map of human fPolλ. Residues 0-575 are encoded by the fPolλ gene. The protein contained N-terminal and C-terminal hexahistidine tags. The tryptic peptide peaks that were detected by our MALDI-ToF instrument are underlined. Arrow heads indicate that the peptide sequence continues on the next lower line at the arrow tail. Protein domains are colored as follows: Yellow, N-terminal nuclear localization sequence and hexahistidine tag; Orange, BRCT domain; Grey, Proline-rich domain; Purple, dRPase domain; Blue, Fingers subdomain; Red, Palm subdomain; Green, Thumb subdomain and C-terminal hexahistidine tag.