Skip to main content
. 2009 Jun 19;297(2):H533–H539. doi: 10.1152/ajpheart.00237.2009

Fig. 2.

Fig. 2.

Increases in Crk-associated substrate (CAS) phosphorylation upon activation with phenylephrine (PE) or angiotensin II (ANG II) are attenuated in arteries from Abl KO mice. Unstimulated or stimulated resistance arteries from Abl−/− or Abl+/+ mice were frozen for biochemical analysis. A: representative immunoblots illustrating CAS phosphorylation (Tyr410) upon PE stimulation (10 μM, 5 min) or ANG II (1 μM, 2.5 min) in tissues from Abl KO and WT mice. B: the level of CAS phosphorylation elicited by PE or ANG II and the level of unstimulated CAS phosphorylation in tissues from KO mice are normalized to the value of unstimulated arteries of WT mice. *P < 0.05, significantly lower PE or ANG II induced CAS phosphorylation in arteries of Abl−/− mice compared with the level of corresponding WT mice. Values represent means ± SE; n = 5 to 6.