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. 2009 Jun 19;297(2):H533–H539. doi: 10.1152/ajpheart.00237.2009

Fig. 4.

Fig. 4.

The increases in F/G-actin ratios upon PE or ANG II stimulation are attenuated by an Abl inhibitor. Carotid arteries from WT mice were treated with 20 μM imatinib for 45 min. These arteries were then stimulated with PE (10 μM, 5 min) or ANG II (1 μM, 2.5 min), or they were US. F/G-actin ratios in tissues were evaluated by fluorescent microscopy as described in materials and methods. F/G-actin ratios in response to various treatments are normalized to the ratio in US arteries not treated with imatinib. *P < 0.05, significantly lower F/G-actin ratios upon contractile stimulation in the presence of imatinib compared with corresponding values obtained from arteries not treated with imatinib. Values are means ± SE; n = 4 to 5.