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Soluble guanylate cyclase (sGC) enzyme activity. Unstimulated (baseline) and 2-(N,N-diethylamino)-diazenolate-2-oxide (DEA-NO)-stimulated sGC enzyme activity in lung extracts of 10- to 12-wk-old wild-type (WT) and sGC-deficient (sGCα1−/−B6) mice. Values are means ± SE (n = 6 for all groups). *P < 0.001 vs. WT DEA-NO. #P < 0.001 vs. baseline.
