Fig. 4.

Changes in arterial blood pressure and heart rate produced by H₂O₂ alone or combined with l-ascorbate injected into the intermediate NTS. A: ABP and HR traces showing the effects of H₂O₂ (500 pmol) into the intermediate NTS before and 20 min after the injection of l-ascorbate (600 pmol) into the same site of an anesthetized rat. Changes in MAP (B) and changes in heart rate (HR) (C) induced by H₂O₂ into the intermediate NTS before and 20 min after ascorbate (AA) injection into the same area (n = 6). Dashed vertical lines in A show the moment of injection into the NTS. Results in B and C are expressed as means ± SE. *Significantly different from before l-ascorbate (P < 0.05, paired t-test).