Fig. 12.

A: in vitro, effects of BQ788 on the release of substance P and PGE₂ produced by 10 pM NE in isolated renal pelvic wall preparations from rats fed the HNa diet. B: effects of BQ123 on the release of substance P and PGE₂ produced by 6,250 pM NE in isolated renal pelvic wall preparations from rats fed the LNa diet. **P < 0.01, vs. baseline; † P < 0.05, NE-induced PGE₂ release in the presence of vehicle vs. BQ788; ‡ P < 0.01 NE-induced substance P release in the presence of vehicle vs. BQ788 (A) and BQ123 (B). CNT, control; REC, recovery.