Table 1.

Effects of SNAP and 8-bromo-cGMP on carbachol-enhanced neonatal bladder strip activity

	Amplitude of SCcarb	Frequency of SCcarb	Inhibition of Amplitude After 30 min	Inhibition of Frequency After 30 min
100 μM SNAP (n =15)	33.2±4%*	10.25±6.2%*	14.9±4.7%*	3.6±10.8%
100 μM 8-bromo-cGMP (n =13)	55.2±2.5%*	28.2±3.8%*	49.2±3.2%*	28.8±3.9%*

Values are means ± SE expressed as percentage of drug-induced reduction measured as percentage of control; n = no. of strips. SNAP, S-nitroso-N-acetyl-dl-penicillamine; SC_carb, carbachol-enhanced spontaneous contractions.

^*P < 0.05 vs. control by Student's t-test with layered Bonferroni corrections when multiple comparisons were made.