Table 2.

Serum parameters in control-1 and FGFR1^−/− mice post-FGF23 administration

	Control-1		FGFR1−/−
	Vehicle	FGF23	Vehicle	FGF23
Serum phosphorus, mg/dl (pre- vs. post-FGF23	5.9±0.4 vs. 6.6±0.3 (n=11)	5.8±0.3 vs. 4.2±0.4*(n=11)	6.2±0.5 vs. 6.9±0.5 (n=8)	5.6±0.3 vs. 5.2±0.5 (n=10)
Serum FGF23, pg/ml	137.8±3.4 (n=6)	809.7±75.2‡ (n=6)	247.0±32.7§ (n=8)	941.1±184.3† (n=10)
Serum 1,25(OH)2D3, pmol/l	87.5±18.7 (n=8)	11.8±0.7‡ (n=10)	86.8±20.1 (n=6)	11.3±0.8‡ (n=7)
Serum PTH, pg/ml	122.8±16.4 (n=13)	107.8±27.4 (n=10)	209.4±42.1§ (n=10)	130.8±15.8 (n=8)

Values are means ± SE; n = no. of mice.

^*P < 0.05, pre vs. post-FGF23.

^†P ≤ 0.005, vehicle vs. FGF23.

^‡P ≤ 0.001, vehicle vs. FGF23.

^§P=0.05, control-1 vehicle vs. FGFR1^−/− vehicle.