Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) As a measure of levels of DSBs after 3 days dox exposure, parental, αKD and αβKD cells were examined by indirect IF for phosphorylated histone H2AX (γH2AX)-containing foci (FITC) in the cell nuclei. As a positive control, the parental cell line was exposed briefly to the topo 2 poison etoposide (10 μM, 30 min). DNA is counterstained with DAPI. Scale bar, 10 μm. (B) Western blot of γH2AX levels over a 4-day time course of dox exposure. α-tubulin is the loading control.
