Table 4.
Family-based association analysis of IPO13 polymorphisms on methacholine hyperresponsiveness (PC20) in childhood asthma.
| Nedocromil/Placebo | Budesonide | |||
| Marker | Number of informative Families | P-value | Number of informative families | P-value |
| rs6671164 | 48 | 0.042 | 16 | 0.504 |
| rs4448553 | 46 | 0.005 | 18 | 0.694 |
| rs1990150 | 21 | 0.094 | 7 | 0.225 |
| rs2240447 | 46 | 0.008 | 18 | 0.498 |
| rs2486014 | 10 | 0.144 | 2 | 0.419 |
| rs2301993 | 47 | 0.004 | 16 | 0.532 |
| rs2301992 | 5 | 0.313 | 2 | 0.621 |
| rs1636879 | 10 | 0.329 | 3 | 0.322 |
| rs7412307 | 38 | 0.108 | 14 | 0.865 |
| rs2428953 | 13 | 0.708 | 5 | 0.221 |
Treatment-stratified analysis of repeated measures of methacholine PC20 performed using FBAT-PC as implemented in PBAT.