. 2009 Jul 20;10(1):67. doi: 10.1186/1465-9921-10-67

Table 6.

Family-based haplotype association analysis of IPO13 polymorphisms on methacholine hyperresponsiveness (PC20) in childhood asthma.

	Nedocromil/Placebo (global p-value = 0.02)		Budesonide (global p-value = 0.58)
Haplotype	Number of informative families	P-value	Number of informative families	P-value

A	136	0.41	53	0.33

B	84	0.02	33	0.53

C	69	0.17	20	0.41

D	43	0.48	18	0.50

Haplotype analysis was performed using one of several haplotype-tagging SNP combinations: rs6671164 – rs199150 – rs2428953. The haplotype designations A through D correspond to those illustrated in Figure 1.