Table 5.

Multivariate RR (95% CI) of total CHD by quintiles of aMED stratified by selected cardiovascular risk factors.

	Q1	Q2	Q3	Q4	Q5	P trend	P interaction
BMI<25 (case=1054)	1	0.89 (0.73-1.06)	0.73 (0.60-0.89)	0.74 (0.61-0.90)	0.57 (0.46-0.71)	<0.0001
BMI>=25 (case=1338)	1	0.96 (0.81-1.14)	0.99 (0.84-1.18)	0.99 (0.83-1.19)	0.84 (0.69-1.02)	0.08	0.005
Physical activity>median (case=880)	1	0.97 (0.77-1.23)	0.86 (0.67-1.09)	0.92 (0.73-1.16)	0.77 (0.60-0.98)	0.006
Physical activity=<median (case=1511)	1	0.90 (0.78-1.05)	0.88 (0.76-1.03)	0.83 (0.70-0.97)	0.66 (0.55-0.80)	<0.0001	0.56
Non smokers (case=1921)	1	0.88 (0.76-1.01)	0.81 (0.70-0.94)	0.80 (0.69-0.93)	0.66 (0.56-0.77)	<0.0001
Current smokers (case=470)	1	0.99 (0.76-1.28)	0.97 (0.73-1.29)	1.05 (0.78-1.42)	0.81 (0.56-1.17)	0.37	0.16
No history of HTN (case=2011)	1	0.91 (0.80-1.04)	0.84 (0.73-0.96)	0.85 (0.74-0.98)	0.70 (0.60-0.81)	<0.0001
History of HTN (case=380)	1	0.91 (0.64-1.29)	0.95 (0.66-1.35)	0.95 (0.66-1.35)	0.83 (0.57-1.22)	0.63	0.14
No history of hypercholesterolemia (case=2235)	1	0.95 (0.84-1.08)	0.87 (0.76-0.99)	0.87 (0.76-1.00)	0.70 (0.60-0.81)	<0.0001
History of hypercholesterolemia (case=156)	1	0.41 (0.21-0.80)	0.67 (0.37-1.21)	0.52 (0.28-1.97)	0.58 (0.31-1.06)	0.33	0.60
Family history of CHD (case=1695)	1	0.92 (0.80-1.07)	0.89 (0.77-1.04)	0.86 (0.73-1.00)	0.71 (0.60-0.84)	<0.0001
No family history of CHD (case=696)	1	0.98 (0.77-1.24)	0.84 (0.65-1.07)	0.94 (0.73-1.20)	0.76 (0.58-0.99)	0.03	0.89

^*adjusted for the same variables as in table 2, except for the variable of stratification.