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. 2009 Jul 28;10:75. doi: 10.1186/1471-2199-10-75

Table 1.

Alternative uPAR splicing identified in the RACE analyses

Variant 5'Donor site 3'Acceptor site Implication
E3 deletion GCGCTTGTGGGAAG GCCGGGCTGTCAC In frame deletion, removal of 48 residues
E4+5 deletion CCAGGGCAACTCTG TCCTGGAGCTTGA In frame deletion, removal of 100 residues, valine insertion
E5 deletion AGGTGAAGAAG TCCTGGAGCTTGA In frame deletion, removal of 46 residues, valine insertion
E6 deletion
(with E7)
CAACGAGGGCCCAA AACCGAAAAACC In frame deletion, removal of 50 residues, lysine insertion
E6 deletion
(with E7b)
CAACGAGGGCCCAA AACGCTCACTCTGG In frame deletion, removal of 50 residues, lysine insertion
E5+6 deletion
(with E7)
AGGTGAAGAAG AACCGAAAAACC In frame deletion, removal of 94 residues
E3+4+5 deletion GCGCTTGTGGGAAG TCCTGGAGCTTGA In frame deletion, removal of 148 residues, valine insertion

uPAR variants detected at >5% frequency in RACE analysis are included.