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. 2009 Jul 29;7:66. doi: 10.1186/1479-5876-7-66

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Copyright © 2009 Kiernan et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Cell delivery improves vasoreactivity. Human CD34+ cell delivery improves endothelium-dependent vasoreactivity after arterial injury. Carotid rings from CD34+ cell treated rats (open squares) show markedly enhanced vasoreactivity to acetylcholine 4 weeks after injury compared to saline controls (diamonds)(P < 0.05 for CD34+ cells vs. saline). However, uninjured left carotid arteries retained the largest relaxation responses (P < 0.05, vs. CD34+ treated rings). Values are means ± SE. n = 8/group.