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Schwann cell migration. In the nerve autograft (a), Schwann cells (SCs) in the graft support the survival. b In the nerve allograft, host Schwann cells (SCs) migrate from both proximal and distal host nerve into the donor graft. c Under adequate immunosuppression, the host SCs coexist with donor SCs within the allograft and support axonal regeneration through the graft. d Once immunosuppression is stopped, the host SCs migrate across the entire graft and replace the donor SCs.
