Table 3.
Summary measures for secondary QL endpoints
| Scale | Statistic | Summary measure | IF | CF | P-value |
|---|---|---|---|---|---|
| aGlobal health status\QL | N | 116 | 101 | ||
| Mean (SD) | Minimum | 55.06 (21.90) | 51.24 (21.19) | 0.259 | |
| Maximum | 68.75 (21.92) | 62.38 (24.05) | 0.062 | ||
| Mean | 62.41 (20.05) | 56.95 (21.10) | 0.061 | ||
| aPhysical functioning | N | 117 | 101 | ||
| Mean (SD) | Minimum | 72.19 (23.47) | 66.01 (24.57) | 0.050 | |
| Maximum | 86.15 (15.98) | 75.70 (23.14) | <0.001 | ||
| Mean | 79.60 (17.68) | 71.05 (22.55) | 0.003 | ||
| aSocial functioning | N | 116 | 102 | ||
| Mean (SD) | Minimum | 66.45 (29.52) | 62.77 (28.90) | 0.329 | |
| Maximum | 84.34 (20.88) | 76.80 (28.04) | 0.053 | ||
| Mean | 76.28 (22.25) | 70.62 (26.72) | 0.164 | ||
| bPain | N | 117 | 102 | ||
| Mean (SD) | Minimum | 13.96 (23.16) | 19.44 (27.03) | 0.092 | |
| Maximum | 31.48 (29.40) | 31.73 (30.65) | 0.970 | ||
| Mean | 21.54 (23.24) | 24.65 (26.51) | 0.500 | ||
| bNausea\vomiting | N | 116 | 102 | ||
| Mean (SD) | Minimum | 7.76 (16.07) | 15.06 (22.32) | 0.001 | |
| Maximum | 21.12 (22.56) | 27.12 (27.40) | 0.150 | ||
| Mean | 13.62 (16.80) | 20.82 (23.06) | 0.026 | ||
| aEQ-5D thermometer | N | 87 | 69 | ||
| Mean (SD) | Minimum | 67.98 (19.18) | 58.32 (18.68) | 0.003 | |
| Maximum | 78.91 (16.10) | 70.76 (19.08) | 0.002 | ||
| Mean | 73.66 (16.56) | 64.80 (17.49) | 0.002 | ||
| aEQ-5D HUI | N | 86 | 66 | ||
| Mean (SD) | Minimum | 0.69 (0.29) | 0.58 (0.29) | 0.003 | |
| Maximum | 0.82 (0.21) | 0.73 (0.29) | 0.110 | ||
| Mean | 0.76 (0.23) | 0.66 (0.27) | 0.018 |
aA higher score represents a higher level of functioning and a better QL
bA higher score represents a higher level of symptom