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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Mol Immunol. 2009 Jun 11;46(13):2706–2713. doi: 10.1016/j.molimm.2009.05.024

Fig. 4.

Fig. 4

The C/EBP site in the TNFR1 promoter is required for activation by C/EBPα and C/EBPβ. HeLa cells were transfected with the wildtype TNFR1p-CAT construct (-154 to +35) or a mutant construct (TNFR1p-CAT ΔC/EBP) in which the C/EBP site was specifically altered, in the presence or absence of co-transfected C/EBPα (A), or C/EBPβ (B) expression vectors. The relative CAT activity in each condition is shown (activity of promoter plus vector control is set as 1). All values in (A) and (B) are given as mean ± standard deviation of duplicate conditions. Two independent experiments showed similar results.