Table 2. ERA PB phospho-signaling is distinguished from OA PB in the CD4+ and CD20+ cell populations.
Phospho-signaling effector | CD4+* | CD8+* | CD20+* |
p-AKT | 50% | 0% | 40% |
p-BTK | 50% | 0% | 40% |
p-CBL | 60% | 0% | 40% |
p-JNK | 50% | 0% | 0% |
p-PLCγ | 60% | 0% | 40% |
p-STAT1 | 50% | 0% | 40% |
p-STAT3 | 40% | 0% | 0% |
p-STAT6 | 40% | 0% | 40% |
p-ZAP70 | 50% | 0% | 40% |
Percentage of ERA patients with MFI values ≥10% above the maximum level recorded in the OA patient cohort is denoted.