Fig. 8.

Effects of dietary supplementation of AA. AIN93G diet with or without 0.4% AA were fed to +/+ and −/− females (n = 3 each). Groups without AA were terminated at 4 months of age, whereas AA supplemented groups were terminated at 8 months of age. A: AA levels in total skin lipid extracts. B: PGD₂ from skin samples. Values are shown relative to the nonsupplemented +/+ group. C: Fatty acid profile of brain total lipid extracts from AA supplemented animals. *P < 0.05; ^†P < 0.01; ^‡ P < 0.001 by Student's t-test.