Fig. 4.

Relationship between apoCI, triglycerides, CETP mass concentration, and cholesteryl ester transfer activity in plasma of normolipidemic rabbits (left) and humans (right). Triglycerides were assayed by an enzymatic method. ApoCI and CETP concentrations were measured by specific ELISAs, and CETP activity was quantitated using a fluorescent assay measuring the transfer of fluorescent NBD-labeled cholesteryl esters from liposome donors to endogenous lipoprotein acceptors in total human plasma (see Materials and Methods). Specific CETP activity was calculated as the ratio of cholesteryl ester transfer activity to CETP mass concentration. Correlation coefficients were calculated by linear regression analysis.