Table 3.

Causes of death^*

Cause of death	Sequential arm, No. (%)	Alternating arm, No. (%)
Cancer progression†	61 (49)	63 (52)
All complications
Toxic effects	9	4
Infection	6	2
Postoperative death	1	1
Second primary cancer	19 (15)	17 (14)
Not cancer related	17 (14)	22 (18)
Unknown	12 (10)	13 (11)

^*There were a total of 125 patients in the sequential arm and a total of 122 patients in the alternating arm who were known to be dead by the time of analysis.

^†Cancer progression included local and/or regional, and/or distant progression.