Table 4.

Patterns of treatment failure among 224 patients in the sequential arm and 226 patients in the alternating arm^*

Type of treatment failure	Time of cumulative incidence estimate, y	Cumulative incidence estimate, % (95% CI)
		Sequential arm	Alternating arm
Locoregional progression	3	28.7 (22.8 to 34.7)	30.3 (24.3 to 36.3)
	5	31.8 (25.6 to 38.0)	32.3 (26.1 to 38.5)
Distant progression	3	13.1 (8.7 to 17.5)	18.3 (13.2 to 23.3)
	5	15.5 (10.7 to 20.3)	21.5 (16.0 to 27.0)
Second primary cancer	3	9.9 (6.0 to 13.9)	11.6 (7.4 to 15.8)
	5	13.3 (8.6 to 17.9)	20.2 (14.6 to 25.8)

^*CI = confidence interval.