Table 3.
Results of histological analysis of the umbilical cord, chorionic plate and placental membranes for acute inflammation
| Variable | All | Groups | P value | ||
|---|---|---|---|---|---|
| MR 0 | MR 1–2 | MR 3–4 | |||
| n=81 | n=11 | n=21 | n=49 | ||
| Funisitis, grades‡ | 0 [0–3] | 0 [0–0] | 0 [0–0] | 3 [0–4] | < 0.001 |
| Funisitis grade distribution§ | < 0.001 | ||||
| grade 0 (absent) | 43 (53) | 9 (11) | 18 (22) | 16 (20) | |
| grade 1 | 5 (6) | 1 (1) | 1 (1) | 3 (4) | |
| grade 2 | 5 (6) | 0 (0) | 1 (1) | 4 (5) | |
| grade 3 | 10 (12) | 1 (1) | 0 (0) | 9 (11) | |
| grade 4 | 18 (22) | 0 (0) | 1 (1) | 17 (21) | |
| Chorioamnionitis, stages‡ | 2 [0–3] | 0 [0–1] | 0 [0–1] | 3 [2–3] | < 0.001 |
| Chorioamnionitis stage distribution § | < 0.001 | ||||
| Stage 0 (absent) | 22 (27) | 7 (9) | 11 (14) | 5 (5) | |
| Stage I | 10 (12) | 2 (2) | 5 (6) | 3 (4) | |
| Stage II | 12 (15) | 1 (1) | 1 (1) | 10 (12) | |
| Stage III | 37 (46) | 1 (1) | 4 (5) | 32 (40) | |
| Amnionitis, grades‡ | 2 [0–3] | 0 [0–0] | 0 [0–0] | 3 [2–3] | < 0.001 |
| Amnionitis gr. 2–4 § | 43 (53) | 10 (9) | 4 (19) | 38 (78) | < 0.001 |
| Choriodeciduitis, grades‡ | 3 [2–3] | 0 [0–2] | 1 [0–3] | 3 [2–3] | < 0.001 |
| Choriodeciduitis gr. 2–4 § | 62 (57) | 5 (45) | 10 (48) | 47 (98) | < 0.001 |
‡
Data presented as median [interquartile range] and analyzed by Kruskal-Wallis ANOVA among the 3 groups.
§
Data presented as n (%) and analyzed by Chi square among all groups. MR: mass restricted score