Table 2.
Genes associated with Parkinson's disease linkage (PARK loci)
| PARK | Gene symbol | GenBank ID | Description | Fold change | P-value |
|---|---|---|---|---|---|
| PARK1 | SNCA | BG260394 | Synuclein, alpha (non A4 component of amyloid precursor) | −1.85899 | 0.00037 |
| PARK5 | UCH-L1 | NM_004181 | Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | −1.94417 | 0.00409 |
| HIP2 | NM_005339 | Huntingtin interacting protein 2 | −1.22173 | 0.00218 | |
| PARK6 | PINK1 | AF316873 | PTEN induced putative kinase 1 | −2.15839 | 0.00010 |
| PARK7 | DJ-1 | NM_007262 | Parkinson disease (autosomal recessive, early onset) 7 | −8.55534 | 0.00048 |
| PARK9 | ATP13A2 | NM_022089 | ATPase type 13A2 | −1.37797 | 0.00432 |
| PARK10 | RAP1GA1 | AB007943 | RAP1 GTPase activating protein | 1.42168 | 0.00045 |
| RIMS1 | AF263310 | Regulating synaptic membrane exocytosis 1 | 1.22118 | 0.00142 | |
| RIMS3 | NM_014747 | Regulating synaptic membrane exocytosis 3 | −2.88055 | 0.00132 |