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. 2009 Jun 30;132(8):2265–2276. doi: 10.1093/brain/awp169

Table 3.

Clinical follow-up

Patient Time to clinical follow-up (mo) NIS at initial eval (points) NIS at follow-up eval (points) Dyck Score QST NCS/EMG CMAP (mV) initial eval CMAP (mV) follow-up MRI
 1 12 12.25 13.75 3 HS vibration Slight progression 11.4 10.7 No change
 2 10 12 11 3 HA heat pain Slight progression 12.8 11.2 No change
 3 20 30 32.75 4 No Change 0 0.0 No change
 4 61 7 10 3 No change
 6 57 20 21 No Change 0 0.0 No change
12 77 2 3.25 3 No change
14 41 19 20.25 4 HS vibration and heat pain Slight progression 11 9.9 No change
15 247 21.5 49 Progression 8.2 0.0
16 48 6 1 2 HS vibration Improvement 2.1 4.8 No change
18 24 22 24 4 HS vibration No Change 6 6.4 No change
19 54 12 17 3 Improvement 13 16.6 No change
25 33 18 Slight progression 0.4 0.0
27 56 8 No Change 0 0.0
29 14 13 12.75 5 HS vibration, HA heat pain No Change 9.8 9.4 No change
Number 15 15 12 10 6 12 12 12 11
Median 44.5 12.6* 15.4* 3 7.1* 5.6*
Range 10–247 2–30 1–49 2–5 0–13 0–16.6

NIS = neuropathy impairment score; QST = quantitative sensory testing; NCS/EMG = nerve conduction studies and electromyography; CMAP = compound muscle action potential; HS = hyposensitivity; HA = hyperalgesia.

*P-values for change over time not significant using paired t-tests.