Table 3.
Patient | Time to clinical follow-up (mo) | NIS at initial eval (points) | NIS at follow-up eval (points) | Dyck Score | QST | NCS/EMG | CMAP (mV) initial eval | CMAP (mV) follow-up | MRI |
---|---|---|---|---|---|---|---|---|---|
1 | 12 | 12.25 | 13.75 | 3 | HS vibration | Slight progression | 11.4 | 10.7 | No change |
2 | 10 | 12 | 11 | 3 | HA heat pain | Slight progression | 12.8 | 11.2 | No change |
3 | 20 | 30 | 32.75 | 4 | No Change | 0 | 0.0 | No change | |
4 | 61 | 7 | 10 | 3 | No change | ||||
6 | 57 | 20 | 21 | No Change | 0 | 0.0 | No change | ||
12 | 77 | 2 | 3.25 | 3 | No change | ||||
14 | 41 | 19 | 20.25 | 4 | HS vibration and heat pain | Slight progression | 11 | 9.9 | No change |
15 | 247 | 21.5 | 49 | Progression | 8.2 | 0.0 | |||
16 | 48 | 6 | 1 | 2 | HS vibration | Improvement | 2.1 | 4.8 | No change |
18 | 24 | 22 | 24 | 4 | HS vibration | No Change | 6 | 6.4 | No change |
19 | 54 | 12 | 17 | 3 | Improvement | 13 | 16.6 | No change | |
25 | 33 | 18 | Slight progression | 0.4 | 0.0 | ||||
27 | 56 | 8 | No Change | 0 | 0.0 | ||||
29 | 14 | 13 | 12.75 | 5 | HS vibration, HA heat pain | No Change | 9.8 | 9.4 | No change |
Number | 15 | 15 | 12 | 10 | 6 | 12 | 12 | 12 | 11 |
Median | 44.5 | 12.6* | 15.4* | 3 | 7.1* | 5.6* | |||
Range | 10–247 | 2–30 | 1–49 | 2–5 | 0–13 | 0–16.6 |
NIS = neuropathy impairment score; QST = quantitative sensory testing; NCS/EMG = nerve conduction studies and electromyography; CMAP = compound muscle action potential; HS = hyposensitivity; HA = hyperalgesia.
*P-values for change over time not significant using paired t-tests.