TABLE 3.
Pre-HAART Era, 1993–1995 |
HAART Era, 1996–2001 |
|||
Characteristic | HR (95% CI) | P | HR (95% CI) | P |
Gender | ||||
Male (Ref) | 1.00 | 1.00 | ||
Female | 0.90 (0.79 , 1.03) | .12 | 1.20 (1.03, 1.40) | .02 |
Race/ethnicity | ||||
Non-Hispanic Black | 1.18 (1.06, 1.31) | <.01 | 1.51 (1.26, 1.80) | <.01 |
Non-Hispanic White (Ref) | 1.00 | 1.00 | ||
Hispanic | 0.94 (0.81, 1.09) | >.05 | 1.22 (0.97, 1.53) | .10 |
Mode of transmission | ||||
Male-to-male sexual contact (Ref) | 1.00 | 1.00 | ||
Injection drug use | 0.94 (0.85, 1.04) | .22 | 1.30 (1.14, 1.49) | <.01 |
Heterosexual contact | 0.89 (0.74, 1.08) | .25 | 0.94 (0.76, 1.16) | .54 |
Age at diagnosis, y | ||||
13–29 (Ref) | 1.00 | 1.00 | ||
30–49 | 1.19 (1.05, 1.35) | .01 | 1.23 (1.02, 1.49) | .03 |
≥ 50 | 1.63 (1.38, 1.93) | <.01 | 2.28 (1.82, 1.49) | <.01 |
Opportunistic diseases | ||||
Pneumocystis carinii pneumonia (Ref) | 1.00 | 1.00 | ||
Kaposi's sarcoma | 1.11 (0.79, 1.55) | .55 | 0.99 (0.53, 1.85) | .97 |
Other | 1.15 (0.99, 1.33) | .07 | 1.50 (1.22, 1.86) | .01 |
None | 0.50 (0.43, 0.59) | <.01 | 0.55 (0.44, 0.69) | <.01 |
Note. HAART = highly active antiretroviral therapy; HR = hazard ratio; CI = confidence interval. Cox regression model used to adjust for gender, race/ethnicity, mode of transmission, age at diagnosis, and opportunistic diseases.