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. Author manuscript; available in PMC: 2009 Aug 11.
Published in final edited form as: Transpl Immunol. 2007 Oct 30;18(4):352–360. doi: 10.1016/j.trim.2007.10.001

Figure 1.

Figure 1

Example of an HLAMatchmaker analysis of serum reactivity with a Luminex panel of HLA-DQ heterodimers. This patient had a DQB1*0301, DQA1*0501 mismatched kidney allograft. The upper half of this figure shows eplets on the donor and panel HLA-DQ antigens that are non-self for the patient. Spaces between two commas (, ,) indicate locations of self-eplets. Serum reactivity is shown as MFI (Mean Fluorescence Intensity) values. Reactivity of Luminex preparations that share donor DQ alleles are depicted in bold font. After the negatively reacting alleles have been recorded, the program removes all their presumably no-reactive eplets from the donor and panel alleles. The remaining eplets on reactive alleles are shown in the bottom half of this figure.