Table 5.
Antibody Responses by Allograft Nephrectomy Patients to Eplets on DR1, DR15, DR16 and DR51 Mismatches
| Case | Recipient DR Alleles | Donor Alleles | Mismatched Eplets on Donor Alleles | Mismatched Eplets on Reactive Alleles |
|---|---|---|---|---|
| ADEL-1 | DRB1*0802#; DRB1*1302# | DRB1*1501 | 142M3,26KFD,71QAA,96QV,140A2,149Q | 142M3,71QAA |
| DRB3*0101 | DRB5*0101 | 31QDIY,32IYN,40HFD,135S,74DRAA,96EV,98KN,108T3,120N,140A2,149Q | 31QDIY,40HFD,96EV,108T3 | |
| ADEL-2 | DRB1*0401# | DRB1*1501# | 142M3,32FYN,47DFR,48FR,71QAA,96QV,98KS,120S | 142M3,32FYN,71QAA |
| DRB4*0101 | DRB5*0101 | 31QDIY,40HFD,67FR,70FDRA,71DRA,74DRAA,96EV,108T3 | 31QDIY,70FDRA,108T3 | |
| AV | DRB1*0801; DRB1*0901 | DRB1*1501 | 142M3,25HRF,26KFD,47DFR,48FR,71QAA,73AADT,96QV | 142M3,71QAA |
| DRB4*0101 | DRB5*0101 | 25HRF,31QDIY,73AADT,74DRAA,96EV,108T3 | none | |
| EM | DRB1*0803; DRB1*1303 | DRB1*1501 | 142M3,26KFD,47DFR,48FR,71QAA,85VV,96QV | 142M3,71QAA,96QV |
| DRB3*0202 | DRB5*0101 | 31QDIY,32IYN,40HFD,135S,67FR,70FDRA,74DRAA,96EV,98KN,108T3,120N | 31QDIY,40HFD,74DRAA,96EV,108T3 | |
| HC | DRB1*0301; DRB1*0404 | DRB1*1501 | 142M3,32FYN,71QAA,96QV | 142M3,71QAA,96QV |
| DRB3*0101; DRB4*0101 | DRB5*0101 | 31QDIY,40HFD,67FR,70FDRA,71DRA,74DRAA,96EV,108T3 | 31QDIY,40HFD,67FR,70FDRA,71DRA,74DRAA,96EV,108T3 | |
| ND11 | DRB1*0401; DRB1*0701 | DRB1*1501 | 142M3,47DFR,48FR,71QAA,96QV,98KS | 142M3,71QAA |
| DRB4*0101 | DRB5*0101 | 31QDIY,40HFD,67FR,70FDRA,71DRA,74DRAA,96EV,108T3 | 31QDIY,40HFD,96EV,108T3 | |
| RM 70532482 | DRB1*0301#; DRB1*0801# | DRB1*1501# | 142M3,25HRF,26KFD,71QAA,73AADT,96QV | 142M3,71QAA,96QV |
| DRB3*0101 | DRB5*0101 | 25HRF,31QDIY,32IYN,40HFD,135S,73AADT,74DRAA,96EV,98KN,108T3,120N | 31QDIY,40HFD,96EV,108T3 | |
| SA | DRB1*0401#; DRB1*1301# | DRB1*1501# | 142M3,32FYN,71QAA,96QV | 142M3,71QAA,96QV |
| DRB3*0202#; DRB4*0101 | DRB5*0101# | 31QDIY,40HFD,67FR,70FDRA,71DRA,74DRAA,96EV,108T3 | 31QDIY,40HFD,96EV,108T3 | |
| ZS | DRB1*0301#; DRB1*1101# | DRB1*1501 | 142M3,26KFD,71QAA,96QV | 142M3,71QAA,96QV |
| DRB3*0202# | DRB5*0101 | 31QDIY,32IYN,40HFD,135S,96EV,98KN,108T3,120N | 31QDIY,32IYN,40HFD,135S,96EV,98KN,108T3 | |
| 2910 | DRB1*0405; DRB1*1101 | DRB1*1601 | 142M3,96QV | 142M3,96QV |
| DRB3*0202; DRB4*0101 | DRB5*0202 | 6C,31QGIY,40HFD,71QAA,81HA,96EV,108T3 | 6C,31QGIY,40HFD,71QAA,96EV,108T3 | |
| POL-8790 | DRB1*0301; DRB1*0802 | DRB1*1602 | 142M3,25HRF,26KFD,67LR,70LDRA,73AADT,74DRAA,96QV | 142M3,70LDRA,96QV |
| DRB3*0101 | DRB5*0202 | 6C,25HRF,31QGIY,32IYN,40HFD,71QAA,73AADT,81HA,96EV,98KN,108T3,120N | 6C,31QGIY,32IYN,40HFD,71QAA,96EV,98KN,108T3 | |
| 4765 | DRB1*0404; DRB1*0701 DRB4*0101 | DRB1*0102 | 12LKF2,14FEH,25HRL,26RL,81HA,96EV,98KS | 12LKF2,96EV |
| 290544 | DRB1*0403#; DRB1*0803# DRB4*0103# | DRB1*0101 | 12LKF2,14FEH,25HRL,26RL,40EFD,47EYR,73AADT,74QRAA,96EV | 12LKF2,14FEH,25HRL,74QRAA96EV |
| 695723 | DRB1*1202#; DRB1*1401# DRB3*0202#; DRB3*0301# | DRB1*0101 | 12LKF2,14FEH,25HRL,32IYN,33LYNQ,71QRA,74QRAA,96EV | 12LKF2,14FEH,25HRL,32IYN,96EV |
| ECU-1 | DRB1*1101; DRB1*1303 DRB3*0202 | DRB1*0101 | 12LKF2,14FEH,25HRL,26RL,32IYN,67LR,71QRA,74QRAA,96EV | 12LKF2,14FEH,25HRL,32IYN,96EV |
| MC 05048330 | DRB1*0301#; DRB1*0804# | DRB1*0101# | 12LKF2,14FEH,25HRL,26RL,32IYN,40EFD,47EYR,67LR,71QRA,73AADT,74QRAAA,96EV | 12LKF2,96EV |
| DRB3*0101 | DRB1*0103# | 12LKF2,14FEH,25HRL,26RL,32IYN,40EFD,47EYR,71DEA,73AADT,74DEAA,96EV | 12LKF2,96EV | |
| ND4 | DRB1*0402; DRB1*1302 DRB3*0301; DRB4*0101 | DRB1*0101 | 12LKF2,14FEH,25HRL,26RL,71QRA,74QRAA,96EV | 12LKF2,14FEH,25HRL,96EV |
| SM | DRB1*0401; DRB1*1401 DRB3*0202; DRB4*0101 | DRB1*0101 | 12LKF2,14FEH,25HRL,26RL,71QRA,74QRAA,96EV | 12LKF2,14FEH,25HRL,96EV |
| VS | DRB1*0701#; DRB1*1401# DRB3*0202#; DRB4*0101 | DRB1*0101# | 12LKF2,14FEH,25HRL,26RL,71QRA,73AADT,74QRAA,96EV | 12LKF2,14FEH,25HRL,71QRA,74QRAA,96EV |
#
Indicates high-resolution typing performed by submitting laboratory