Table 1.
Values at baseline assessment on FAQ, FBI, FTLD-CDR, standard CDR, NPI, and cognitive tests by syndrome
| Instrument | bvFTD |
PNFA |
PLA |
SMD |
ALLa |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | |
| FTLD-CDR (eight domains) | 47 | 6.79 (3.60) | 25 | 4.18 (2.88) | 9 | 2.94 (1.74) | 26 | 6.00 (4.51) | 98 | 5.91 (3.82) |
| Standard CDR (six domains) | 46 | 4.64 (3.09) | 25 | 2.26 (2.25) | 9 | 2.83 (2.25) | 26 | 3.85 (3.71) | 97 | 3.81 (3.20) |
| FAQ | 46 | 16.22 (8.86) | 24 | 7.62 (7.58) | 9 | 10.33 (8.47) | 26 | 11.46 (8.99) | 96 | 12.78 (9.24) |
| FBI | 43 | 26.81 (12.72) | 25 | 12.00 (9.05) | 9 | 8.44 (5.25) | 26 | 17.69 (12.36) | 94 | 20.35 (13.24) |
| NPI | 46 | 30.17 (18.8) | 25 | 10.68 (12.48) | 9 | 5.56 (3.91) | 26 | 20.50 (19.25) | 97 | 22.56 (19.15) |
| Sum of learning over four trials | 47 | 19.72 (6.34) | 25 | 16.56 (10.19) | 9 | 13.44 (8.57) | 26 | 13.38 (7.47) | 98 | 17.23 (8.14) |
| Delayed free recall | 47 | 3.26 (2.90) | 24 | 4.17 (2.97) | 9 | 2.67 (2.87) | 26 | 1.65 (2.38) | 97 | 3.05 (2.91) |
| Delayed recognition | 47 | 7.91 (1.23) | 24 | 7.42 (1.98) | 9 | 8.44 (0.73) | 26 | 5.92 (2.42) | 97 | 7.26 (1.97) |
| Trailmaking (s) | 47 | 66.66 (39.54) | 24 | 80.38 (40.62) | 9 | 102.33 (29.29) | 26 | 56.65 (33.38) | 97 | 67.37 (38.84) |
| Trailmaking (number correct) | 47 | 11.45 (4.34) | 24 | 9.88 (5.15) | 9 | 10.78 (4.63) | 26 | 12.85 (2.84) | 97 | 11.43 (4.32) |
| Number cancellation (number correct) | 44 | 26.16 (11.47) | 25 | 21.52 (10.91) | 9 | 22.11 (9.39) | 26 | 28.27 (7.96) | 95 | 25.52 (10.67) |
| Digits backwards | 46 | 3.87 (1.51) | 24 | 2.46 (1.25) | 9 | 2.78 (1.20) | 26 | 4.31 (1.29) | 96 | 3.64 (1.55) |
| Stroop colour word (number correct) | 43 | 44.26 (21.97) | 23 | 31.48 (16.82) | 9 | 33.89 (13.83) | 26 | 40.42 (20.82) | 92 | 39.98 (20.91) |
| Digit symbol substitution | 45 | 45.84 (18.79) | 24 | 38.12 (18.41) | 9 | 38.33 (20.57) | 26 | 51.73 (19.27) | 95 | 45.51 (19.28) |
| Letter fluency | 45 | 22.98 (13.71) | 23 | 12.83 (8.68) | 9 | 18.78 (9.60) | 26 | 21.00 (11.46) | 94 | 19.95 (12.62) |
| Category fluency | 47 | 25.32 (10.91) | 24 | 20.42 (11.70) | 9 | 19.44 (9.58) | 26 | 14.35 (12.73) | 97 | 21.16 (12.38) |
| Confrontation naming | 46 | 23.37 (6.37) | 24 | 19.54 (9.02) | 9 | 14.22 (8.98) | 25 | 6.12 (5.97) | 95 | 17.86 (10.03) |
| Verbal similarities | 44 | 15.16 (6.33) | 23 | 14.00 (8.17) | 9 | 10.44 (4.56) | 26 | 9.81 (8.00) | 93 | 13.38 (7.57) |
| MMSE | 47 | 25.13 (4.33) | 25 | 22.04 (6.07) | 9 | 22.33 (3.67) | 26 | 23.73 (4.65) | 98 | 23.97 (5.02) |
FTLD-CDR = 8-domain CDR scale; Standard CDR = 6-domain CDR scale.
aALL patients excluding PLA.