Table 2.
GO enrichment.
| TP | Factors | GO term | GO description | annotated | p-value | |
| 28 | 9 | GO:0001889 | BP | liver development | 5/7 | 4.7e-06 |
| TP | Targets | GO term | GO description | annotated | p-value | |
| 2 | 669 | GO:0004842 | MF | ubiquitin-protein ligase activity | 16/121 | 8.7e-06 |
| 2 | 669 | GO:0051216 | BP | cartilage development | 12/71 | 9.0e-06 |
| 3 | 1474 | GO:0005550 | MF | pheromone binding | 11/27 | 2.8e-06 |
| 4 | 1419 | GO:0005132 | MF | interferon-alpha/beta receptor binding | 7/8 | 1.2e-07 |
| 5 | 1510 | GO:0005132 | MF | interferon-alpha/beta receptor binding | 6/8 | 7.3e-06 |
| 12 | 198 | GO:0000786 | CC | nucleosome | 14/136 | 4.2e-10 |
| 12 | 198 | GO:0005634 | CC | nucleus | 84/4115 | 8.2e-08 |
| 12 | 198 | GO:0003677 | MF | DNA binding | 54/1993 | 4.0e-07 |
| 12 | 198 | GO:0003697 | MF | single-stranded DNA binding | 6/37 | 4.2e-06 |
| 12 | 198 | GO:0006334 | BP | nucleosome assembly | 14/147 | 1.9e-09 |
| 12 | 198 | GO:0006260 | BP | DNA replication | 16/151 | 2.4e-06 |
| 13 | 372 | GO:0004984 | MF | olfactory receptor activity | 50/1001 | 5.4e-09 |
| 13 | 372 | GO:0007186 | BP | G-protein coupled receptor protein signa... | 81/1968 | 1.4e-09 |
| 15 | 230 | GO:0034097 | BP | response to cytokine stimulus | 5/15 | 1.0e-06 |
| 18 | 268 | GO:0004984 | MF | olfactory receptor activity | 43/1001 | 6.0e-11 |
| 18 | 268 | GO:0007166 | BP | cell surface receptor linked signal tran... | 74/2606 | 2.4e-08 |
| 18 | 268 | GO:0007608 | BP | sensory perception of smell | 10/90 | 7.9e-07 |
| 25 | 275 | GO:0004556 | MF | alpha-amylase activity | 4/5 | 2.1e-07 |
| 28 | 167 | GO:0007186 | BP | G-protein coupled receptor protein signa... | 38/1968 | 4.1e-06 |
| 55 | 54 | GO:0032183 | MF | SUMO binding | 2/2 | 1.0e-05 |
We tested each of the factors and target genes associated with each of the 68 transcriptional programs for enrichment of GO terms across the three GO ontologies: biological process (BP), molecular function (MF) and cellular component (CC). The number of factors (resp. targets) associated with the program is displayed followed by information about the GO term. 'Annotated' shows the number of factors (resp. targets) annotated with the term in the program compared to the total numbers of factors (resp. targets) annotated with the term. The p-values are not corrected for multiple testing. Based on a bootstrap analysis described in the Methods section any p-value below 1e-04 might be deemed significant at the 0.01 level.