Table 1.
| Cingulate cortex (BA 33) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Diagnosis | N | Age | PMI | Gender | Hemisphere | APD | MS | ADD |
| Years | Hours | M / F | L / R | % | % | % | ||
| Bipolar | 15 | 74.3±2.29 | 22.5±2.40 | 4 / 11 | 9 / 6 | 80% (4/5) | 60% (3/5) | 40% (2/5) |
| Schizophrenia | 22 | 67.8±2.94 | 20.6±1.71 | 9 / 13 | 8 / 14 | 64% (7/11) | 36% (4/11) | 36% (4/11) |
| Control | 45 | 69.8±1.87 | 23.2±0.85 | 24 / 21 | 21 / 24 | 0 | 0 | 0 |
| Cingulate cortex for nuclei counts | ||||||||
|---|---|---|---|---|---|---|---|---|
| Years | Hours | M / F | L / R | % | % | % | ||
| Schizophrenia | 6 | 69.5±6.53 | 24.0±2.44 | 2 / 4 | 3 / 3 | 80% (4/5) | 40% (2/5) | 20% (1/5) |
| Control | 5 | 71.8±6.68 | 21.5±4.10 | 2 / 3 | 2 / 3 | 0 | 0 | 0 |
| Dorsolateral prefrontal cortex (BA 9) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Years | Hours | M / F | L / R | % | % | % | ||
| Schizophrenia | 6 | 69.2±6.60 | 21.5±2.52 | 3 / 3 | 4 / 2 | 100% (4/4) | 50% (2/4) | 25% (1/4) |
| Control | 6 | 66.7±6.10 | 25.4±2.67 | 3 / 3 | 3 / 3 | 0 | 0 | 0 |
| Prefrontal cortex (BA 10) | |||||
|---|---|---|---|---|---|
| Age Range | Hours | M / F | L / R | ||
| Perinatal / infant | 4 | 40 ewg - 9 months | 15±6.58 | 2 / 2 | 4 / 0 |
| Child & adult | 10 | 2 – 51 years | 15.7±6.06 | 6 / 4 | 9 / 1 |
PMI = postmortem interval
ewg = estimated weeks gestation
APD = antipsychotic drugs (typical and atypical)
MS = mood stabilizers (lithium, depakote)
ADD = antidepressant drugs (Zoloft, Paxil, Wellbutrin, Effexor, trazodone, remeron)
Age and PMI expressed as mean ± standard error.