Table 3.
Numbers of Participants and Infections Associated with Individual Studies for Each Hypnotic Drug and Parallel Placebo
| Medication | Received Drug |
Received Placebo |
||||
|---|---|---|---|---|---|---|
| No. | Infections, no. | Infections/participant, % | No. | Infections, no. | Infections/participant, % | |
| Eszopiclone | 2432 | 489 | 20.1 | 1354 | 146 | 10.8 |
| Ramelteon | 2214 | 24 | 1.1 | 1157 | 8 | 0.7 |
| Zaleplon | 2589 | 11 | 0.4 | 947 | 5 | 0.5 |
| Zolpidem | 1593 | 82 | 5.1 | 1309 | 41 | 3.1 |
| TOTALS | 8828 | 606 | 6.9 | 4383* | 200 | 4.6 |
*
The placebo total was corrected for placebo groups contrasted to both zaleplon and zolpidem in 3-way studies.