Table 1.
Clinicopathological findings of IgG4-related sclerosing disease
| Clinicopathological findings | |
| Systemic disease characterized histopathologically by extensive IgG4-positive plasma cell infiltration of various organs together with T lymphocytes | |
| Major clinical manifestations are apparent in the organs in which tissues fibrosis with obstructive phlebitis is pathologically induced | |
| Pancreas | Autoimmune pancreatitis |
| Bile duct | IgG4-related sclerosing cholangitis |
| Gallbladder | IgG4-related sclerosing cholangitis |
| Salivary gland | IgG4-related sclerosing cholangitis |
| Retroperitoneum | IgG4-related retroperitoneal fibrosis |
| Kidney | IgG4-related tubulointerstitial nephritis |
| Lung | IgG4-related interstitial pneumonia |
| Prostate | IgG4-related prostatitis |
| Some inflammatory pseudotumors (liver, lung and hypophysis) may be involved in this disease | |
| Occasional association with lymphadenopathy | |
| Elderly male preponderance | |
| Frequent elevation of serum IgG4 levels | |
| Favorite response to steroid therapy | |
| Differentiation from malignant tumor is important | |
| Precise pathogenesis and pathophysiology remain unclear | |