Figure 4.
Recovery from inactivation. (A) Time course of recovery from inactivation for WT (n=12) and G1631D (n=16) was elicited using the two-pulse protocol shown in the inset. Time constants and fractional amplitudes are given in Table S1. (B) Activity dependent loss of channel availability following trains of 100ms pulses to −10mV from a holding potential of −120mV applied at the frequency indicated (n=10–18 cells). Residual current following the 100th pulse was normalized to the first pulse current amplitude.