Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver

. Author manuscript; available in PMC: 2009 Aug 12.

Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2007 Dec 3;77(5-6):251–261. doi: 10.1016/j.plefa.2007.10.023

Figure 6. Fifteen weeks of n-3 PUFA dietary deprivation, compared with an n-3 PUFA adequate diet, downregulates rat frontal cortex expression of p38 MAP kinase activity and phospho p38 MAP kinase protein, CREB DNA binding activity and phospho-CREB protein, and BDNF protein and mRNA. From 68.