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Antibody response against Ag85B or ESAT-6 in mice immunized with BCG and rBCG. C57BL/6 mice (five mice per group) were immunized with PBS, BCG, rBCG-A-E, or rBCG-AN-E-AC and killed after 6 weeks to prepare serum for examination of the IgG antibody response (a and b) and the ratio of IgG2c/IgG1 (c). The results are expressed as the means ± standard errors.
